People with various urban emotional syndromes often fall into different emotional symptoms, or are depressed, or hysterical, or entangled; four patients with serious love diseases from different backgrounds and in different forms gather at the "Emotional Flu Center" to seek medical treatment. The one who treats them is the spicy love doctor Jiang Hu (played by Jin Shijie), who has created various quaint treatment methods and can always help emotional patients regain their health. Liu Xu (played by Fan Yichen), a "playboy" who broke up with his ex-girlfriend at the emotional flu center, met Tao Ran (played by Chen Jie), a "love cleansing girl" who came for consultation. As a hunter of beauty, Liu Xu couldn't help but fall in love with her, and then used all kinds of tricks to capture Tao Ran. Liu Xu, who has never been defeated in the love field, didn't expect to meet a powerful opponent this time, and the road to chasing girls was full of twists and turns. Another seriously ill patient, who can be called a "fake loser but a real virgin" - Lin Sen (played by Xu Deliang) met Li Yiyi, a gold digger who was in a dilemma of "inability to love". He was attracted by her charm and boasted that he would treat her to a meal for 100,000 yuan. From then on, he embarked on a road of no return of "a man becomes poor for the sake of pleasing others". The four of them tested each other, competed secretly, and hindered each other, and started a series of inextricable love battles, frequently creating various urban jokes. In the end, some people recovered from their illness, while others became more "deadly in love"...