At Xincheng Renhe Hospital, nurse Zhang Shumei was suspected of using the wrong medicine and causing the patient's death and was forced to leave her post. Her 4-year-old daughter was abducted by human traffickers, and Zhang Shumei was killed in a car accident two years later when she was in a trance. Chinese-American surgical expert Zhuang Shu came to Xincheng Renhe Hospital to find out the truth about his mother Zhang Shumei's accident 30 years ago and find his lost sister. The daughter of the deceased, Lu Chenxi, studied under Fu Bowen and grew up to be the attending physician of thoracic surgery. However, she offended the director of thoracic surgery, Yang Fan, because she disliked the interests first and repeatedly offended him and was transferred to the emergency department. It was Zhuang Shu who repeatedly brought the skilled Lu Chenxi back to the thoracic surgery table. As they got along day and night, Zhuang Shu's medical skills amazed Lu Chenxi, and his thoughtful consideration for the patients also made Lu Chenxi reflect. The two gradually fell in love. In the end, Zhuang Shu found his sister, and with the help of Lu Chenxi, he restored the truth of his mother's accident.