Set in 2019, the story will explore two questions: When is kidnapping not kidnapping, and when your wife is not your wife? After an unexpected series of events lands Dorothy 'Dot' Lyon (Juno Temple) in trouble with the authorities, the seemingly typical Midwestern housewife is suddenly thrown back into the life she thought she had left behind. North Dakota Sheriff Roy Tillman (Jon Hamm) has been searching for Dot for a long time. A rancher, preacher, and lawman, Roy believes he is the law, and therefore above it. On Roy's side is his loyal but irresponsible son Gator (Joe Keery), who is desperate to prove himself to his extraordinary father. Unfortunately, Gator is beyond redemption. So, in order to hunt Dot, Roy recruits Ole Munch (Sam Spruell), a drifter with a mysterious origin. As her deepest secrets begin to unravel, Dot tries to protect her family from the damage of her past, but her doting and well-meaning husband Wayne (David Rysdahl) keeps turning to his mother, Lorraine Lyon (Jennifer Jason Leigh), for help. As CEO of the largest debt collection agency in the United States, the Debt Queen is not happy with her son's choice of wife and never misses an opportunity to express her disapproval. However, when Dot's unusual behavior attracts the attention of Minnesota Police Officer Indira Olmstead (Richa Moorjani) and North Dakota Police Officer Witt Farr (Lamorne Morris), Lorraine appoints her in-house legal counsel, Danish Graves (Dave Foley), to help her daughter-in-law. After all, family is family. But Dot has an incredible set of survival skills. Faced with adversity, she is about to show why a person should never anger her mother.