The genius doctor Zheng Ren (played by Zhang Binbin) came to Haicheng Hospital to investigate the truth of the "wrongful case" 18 years ago. He formed a pair of "happy enemies" with Su Yun (played by Dai Xu), the "salted fish" director of the emergency department. They overcame one difficult disease after another with mutual support, and started a "cool, exciting, cool, and hi" medical journey. During this period, Zheng Ren not only uncovered the "cruel truth" of the incident that year, but also formed a "conjoined separation" team with Su Yun, Lin Yuan, Xie Yiren and others. Adhering to the original intention of the angel in white in his heart, under the guidance of repeated simulation training and unswerving medical spirit, he realized the ideal of a doctor who saves lives, cures patients, and warms people's hearts.